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Tdark
ZSCAN2
Zinc finger and SCAN domain-containing protein 2

Protein Summary
Description
May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis. The protein encoded by this gene contains several copies of zinc finger motif, which is commonly found in transcriptional regulatory proteins. Studies in mice show that this gene is expressed during embryonic development, and specifically in the testis in adult mice, suggesting that it may play a role in regulating genes in germ cells. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334141
  • ENSP00000333895
  • ENSG00000176371
  • ENST00000379358
  • ENSP00000368663
  • ENST00000448803
  • ENSP00000410198
  • ENST00000540894
  • ENSP00000441855
  • ENST00000546148
  • ENSP00000445451

Symbol
  • ZFP29
  • ZNF854
  • ZFP29
  • ZNF854
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.84
transcription factor
0.8
gene perturbation
0.77
histone modification site profile
0.73
protein domain
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.87   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 120   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.87   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 120   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (18)
KNDC1
Tdark
Novelty:  0.1459108
Score:  0.562
Data Source:  STRINGDB
TMEM147
Tbio
Novelty:  0.39056101
Score:  0.512
Data Source:  STRINGDB
FEM1B
Tbio
Novelty:  0.06746412
Score:  0.508
Data Source:  STRINGDB
C7orf25
Tdark
Novelty:  3.59798701
Score:  0.472
Data Source:  STRINGDB
WDR73
Tbio
Novelty:  0.10253438
Score:  0.466
Data Source:  STRINGDB
UTF1
Tbio
Novelty:  0.02001499
Score:  0.465
Data Source:  STRINGDB
TM4SF20
Tbio
Novelty:  0.21582226
Score:  0.463
Data Source:  STRINGDB
DEFB129
Tdark
Novelty:  0.26809608
Score:  0.452
Data Source:  STRINGDB
TMBIM4
Tbio
Novelty:  0.00736177
Score:  0.448
Data Source:  STRINGDB
CIZ1
Tbio
Novelty:  0.03730538
Score:  0.447
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
2
12
12
93.5
BMI-adjusted waist circumference
4
6
9
79.7
5
4
1
1.1
76
appendicular lean mass
1
1
1
59.8
glomerular filtration rate
2
1
2
52.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
12
93.5
BMI-adjusted waist circumference
9
79.7
1
1.1
76
appendicular lean mass
1
59.8
glomerular filtration rate
2
52.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 2
VGNC:1574
453604
Macaque
zinc finger and SCAN domain containing 2
695673
Mouse
MGI:99176
22691
Rat
RGD:1584548
683603
Dog
zinc finger and SCAN domain containing 2
VGNC:49770
488749
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger and SCAN domain containing 2
Macaque
zinc finger and SCAN domain containing 2
Mouse
Rat
Dog
zinc finger and SCAN domain containing 2
Publication Statistics
PubMed Score 1.87
PubMed score by year
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Related Publications
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PMID
Year
Title