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Tbio
ABI3BP
Target of Nesh-SH3

Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
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GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.42   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 207   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.42   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 207   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
optic disc size measurement
1
1
1
77.6
optic disc area measurement
2
2
3
64.8
cup-to-disc ratio measurement
2
2
2
63.3
sex hormone-binding globulin measurement
2
1
2
38.2
self reported educational attainment
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
optic disc size measurement
1
77.6
optic disc area measurement
3
64.8
cup-to-disc ratio measurement
2
63.3
sex hormone-binding globulin measurement
2
38.2
self reported educational attainment
1
15.8
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ABI family member 3 binding protein
VGNC:11319
740047
Mouse
MGI:2444583
320712
Rat
RGD:1562717
363767
Dog
ABI family member 3 binding protein
VGNC:37477
478544
Opossum
ABI family member 3 binding protein [Source:HGNC Symbol;Acc:HGNC:17265]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ABI family member 3 binding protein
Mouse
Rat
Dog
ABI family member 3 binding protein
Opossum
ABI family member 3 binding protein [Source:HGNC Symbol;Acc:HGNC:17265]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q7Z7G0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (9)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
BHF-UCL
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (18)
1 – 10 of 18
ABI3
Tbio
Novelty:  0.00891209
Score:  0.975
Data Source:  STRINGDB
ABI1
Tbio
Novelty:  0.00796638
Score:  0.645
Data Source:  STRINGDB
TMEM255B
Tdark
Novelty:  1.57149427
Score:  0.536
Data Source:  STRINGDB
KRBOX1
Tdark
Novelty:  3.9375
Score:  0.533
Data Source:  STRINGDB
LTBP3
Tbio
Novelty:  0.0190763
Score:  0.503
Data Source:  STRINGDB
ATP10B
Tdark
Family:  Transporter
Novelty:  0.11537156
Score:  0.498
Data Source:  STRINGDB
LRRIQ3
Tdark
Novelty:  0.63243484
Score:  0.487
Data Source:  STRINGDB
CCDC80
Tbio
Novelty:  0.01634056
Score:  0.483
Data Source:  STRINGDB
DCAF4L2
Tdark
Novelty:  0.55635961
Score:  0.473
Data Source:  STRINGDB
LTBP2
Tbio
Novelty:  0.013159
Score:  0.462
Data Source:  STRINGDB
Publication Statistics
PubMed Score  15.42

PubMed score by year
PubTator Score  6.35

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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