Tchem GPR142 Probable G-protein coupled receptor 142

Protein Summary

Description

Orphan receptor. GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• Q7Z601
• A4CYJ8
• Q86SL3

Gene Name

• GPR142

Ensembl ID

• ENST00000335666
• ENSP00000335158
• ENSG00000257008

Symbol

• PGR2
• PGR2
• GPRg1b

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.54
cell type or tissue	0.52
cell line	0.49
tissue	0.42
PubMedID	0.41

Protein Classes

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Probable G-protein Coupled Receptor 142

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.43   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 164   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.43   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 164   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 94

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0