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Tbio
HSD17B13
17-beta-hydroxysteroid dehydrogenase 13

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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 34.11   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 34.11   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
1
1
91.6
alcohol abuse
3
1
3
90.5
serum alanine aminotransferase measurement
1
1
1
83.3
liver fibrosis measurement
1
1
1
79
aspartate aminotransferase measurement
1
1
1
78.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
testosterone measurement
1
91.6
alcohol abuse
3
90.5
serum alanine aminotransferase measurement
1
83.3
liver fibrosis measurement
1
79
aspartate aminotransferase measurement
1
78.6
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
hydroxysteroid 17-beta dehydrogenase 13
VGNC:48904
471245
Mouse
MGI:2140804
243168
Rat
RGD:1359553
305150
Dog
hydroxysteroid 17-beta dehydrogenase 13
VGNC:41803
478468
Horse
hydroxysteroid 17-beta dehydrogenase 13
VGNC:18885
100052769
Species
Name
OMA
EggNOG
Inparanoid
Chimp
hydroxysteroid 17-beta dehydrogenase 13
Mouse
Rat
Dog
hydroxysteroid 17-beta dehydrogenase 13
Horse
hydroxysteroid 17-beta dehydrogenase 13
Pathways (3)
Lipid particle organization (R-HSA-8964572)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Lipid particle organization
Reactome
Metabolism
Reactome
Metabolism of lipids
Name
Explore in Pharos
Explore in Source
Lipid particle organization
Metabolism
Metabolism of lipids
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (19)
1 – 10 of 19
TSPAN10
Tdark
Novelty: 0.19962098
p_int: 0.997588923
p_ni: 0.001604625
p_wrong: 0.000806452
Score: 0.68
Data Source: BioPlex,STRINGDB
FANK1
Tbio
Novelty: 0.12389783
Score: 0.59
Data Source: STRINGDB
ECI2
Tbio
Family: Enzyme
Novelty: 0.02317646
Score: 0.565
Data Source: STRINGDB
NBPF3
Tdark
Novelty: 0.43771383
Score: 0.514
Data Source: STRINGDB
ALDH3A2
Tbio
Family: Enzyme
Novelty: 0.0059198
Score: 0.512
Data Source: STRINGDB
PNPLA3
Tbio
Family: Enzyme
Novelty: 0.00180327
Score: 0.498
Data Source: STRINGDB
SULT4A1
Tbio
Family: Enzyme
Novelty: 0.02455678
Score: 0.495
Data Source: STRINGDB
FRRS1
Tdark
Family: Enzyme
Novelty: 0.04371703
Score: 0.473
Data Source: STRINGDB
SLC16A9
Tbio
Family: Transporter
Novelty: 0.06564904
Score: 0.468
Data Source: STRINGDB
HSD17B4
Tbio
Novelty: 0.00547499
Score: 0.465
Data Source: STRINGDB
Publication Statistics
PubMed Score  34.11

PubMed score by year
PubTator Score  123.35

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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