Protein Summary
Negatively regulates cell proliferation and cell migration. The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury. [provided by RefSeq, Jul 2016]
- ENST00000312553
- ENSP00000308315
- ENSG00000174348
- ENST00000371500
- ENSP00000360555
- ENST00000395871
- ENSP00000379212
- ENST00000618387
- ENSP00000479233
- SLRR5A
- PCAN
- SLRR5A
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
tissue sample | 0.72 | ||
small molecule perturbation | 0.61 | ||
histone modification site profile | 0.59 | ||
PubMedID | 0.58 | ||
tissue | 0.57 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 93.59 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 105 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 93.59 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 105 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0