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Tbio
GOLGA7
Golgin subfamily A member 7

Protein Summary
Description
May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357743
  • ENSP00000350378
  • ENSG00000147533
  • ENST00000405786
  • ENSP00000386030
  • ENST00000518270
  • ENSP00000429329
  • ENST00000520817
  • ENSP00000429480

Symbol
  • GCP16
  • GCP16
  • GOLGA7A
  • HSPC041
  • GOLGA3AP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
interacting protein
0.96
kinase perturbation
0.84
cellular component
0.73
transcription factor binding site profile
0.73


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.31   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.31   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (107)
CLDND1
Tbio
Novelty:  0.06681793
p_int:  0.999999715
p_ni:  2.84e-7
p_wrong:  1e-9
Score:  0.784
Data Source:  BioPlex,STRINGDB
HAVCR2
Tbio
Novelty:  0.00155885
p_int:  0.999847129
p_ni:  0.000151751
p_wrong:  0.00000112
Data Source:  BioPlex
SLC1A1
Tchem
Family:  Transporter
Novelty:  0.00218479
p_int:  0.998311616
p_ni:  0.001649344
p_wrong:  0.00003904
Score:  0.177
Data Source:  BioPlex,STRINGDB
MFSD4A
Tdark
Novelty:  0.62186415
p_int:  0.99692175
p_ni:  0.003056347
p_wrong:  0.000021903
Score:  0.188
Data Source:  BioPlex,STRINGDB
TSPAN3
Tbio
Novelty:  0.06362133
p_int:  0.996029024
p_ni:  0.003919696
p_wrong:  0.00005128
Data Source:  BioPlex
GYPA
Tbio
Novelty:  0.00067203
p_int:  0.995696641
p_ni:  0.004267111
p_wrong:  0.000036248
Score:  0.686
Data Source:  BioPlex,STRINGDB
BDH2
Tbio
Family:  Enzyme
Novelty:  0.04118875
p_int:  0.883987213
p_ni:  0.116012787
Data Source:  BioPlex
TPM2
Tbio
Novelty:  0.00406572
p_int:  0.867462435
p_ni:  0.131841149
p_wrong:  0.000696416
Data Source:  BioPlex
ZDHHC9
Tbio
Family:  Enzyme
Novelty:  0.04949094
Score:  0.998
Data Source:  STRINGDB
FOLR3
Tbio
Novelty:  0.04966143
Score:  0.909
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Neutrophil degranulation
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Neutrophil degranulation
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (11)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Traceable Author Statement (TAS)
Reactome
Traceable Author Statement (TAS)
Reactome
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
1
1
6.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
6.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
golgin A7
VGNC:873
464139
Macaque
golgin A7
709911
Mouse
MGI:1931029
57437
Rat
RGD:1359725
361171
Dog
golgin A7
VGNC:41342
607476
Species
Name
OMA
EggNOG
Inparanoid
Chimp
golgin A7
Macaque
golgin A7
Mouse
Rat
Dog
golgin A7
Publication Statistics
PubMed Score 5.31
PubMed score by year
PubTator Score 2.05
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title