You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
MDGA2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2

Protein Summary
Description
May be involved in cell-cell interactions.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357362
  • ENSP00000349925
  • ENSG00000139915
  • ENST00000399232
  • ENSP00000382178
  • ENST00000426342
  • ENSP00000405456

Symbol
  • MAMDC1
  • MAMDC1
  • c14_5286
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
protein domain
0.97
cell line
0.78
phenotype
0.71
microRNA
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.45   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.45   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (95)
1 – 10 of 95
TECTA
Tbio
Novelty:  0.02462336
Score:  0.926
Data Source:  STRINGDB
CNTN4
Tbio
Novelty:  0.02483465
Score:  0.916
Data Source:  STRINGDB
NTM
Tbio
Novelty:  0.01659865
Score:  0.91
Data Source:  STRINGDB
LSAMP
Tbio
Novelty:  0.01237032
Score:  0.909
Data Source:  STRINGDB
CNTN5
Tbio
Novelty:  0.00601105
Score:  0.907
Data Source:  STRINGDB
OPCML
Tbio
Novelty:  0.01569352
Score:  0.907
Data Source:  STRINGDB
LY6H
Tbio
Novelty:  0.10210816
Score:  0.905
Data Source:  STRINGDB
CNTN3
Tbio
Novelty:  0.0055725
Score:  0.904
Data Source:  STRINGDB
MDGA1
Tbio
Novelty:  0.04478487
Score:  0.904
Data Source:  STRINGDB
CD109
Tbio
Novelty:  0.01280272
Score:  0.904
Data Source:  STRINGDB
Pathways (3)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational modification: synthesis of GPI-anchored proteins
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational modification: synthesis of GPI-anchored proteins
Post-translational protein modification
Gene Ontology Terms (4)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Traceable Author Statement (TAS)
Reactome
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
2
2
70.9
age at first sexual intercourse measurement
1
1
1
54.4
2
2
2
37.6
1
1
0
1.1
26.6
mathematical ability
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
70.9
age at first sexual intercourse measurement
1
54.4
2
37.6
0
1.1
26.6
mathematical ability
1
21.5
Find similar targets by:
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
MAM domain containing glycosylphosphatidylinositol anchor 2
VGNC:3384
467448
Macaque
MAM domain containing glycosylphosphatidylinositol anchor 2
703237
Mouse
MGI:2444706
320772
Rat
RGD:735131
314180
Dog
MAM domain containing glycosylphosphatidylinositol anchor 2
VGNC:43102
480310
Species
Name
OMA
EggNOG
Inparanoid
Chimp
MAM domain containing glycosylphosphatidylinositol anchor 2
Macaque
MAM domain containing glycosylphosphatidylinositol anchor 2
Mouse
Rat
Dog
MAM domain containing glycosylphosphatidylinositol anchor 2
Publication Statistics
PubMed Score 14.45
PubMed score by year
PubTator Score 10.63
PubTator score by year