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Tbio
BNIPL
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein

Protein Summary
Description
May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295294
  • ENSP00000295294
  • ENSG00000163141
  • ENST00000368931
  • ENSP00000357927
  • ENST00000485855
  • ENSP00000435072
  • ENST00000650563
  • ENSP00000497659

Symbol
  • BNIPS
  • PP753
  • BNIP-S
  • BNIPL1
  • BNIPL2
  • BNIPL-1
  • BNIPL-2
  • BNIP-Sbeta
  • BNIP-Salpha
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.6
tissue sample
0.59
gene perturbation
0.51
cell line
0.45
tissue
0.44


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.54   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 74   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.54   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0