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Tbio
KRT26
Keratin, type I cytoskeletal 26

Protein Summary
Description
The protein encoded by this gene is a member of the keratin superfamily. This keratin protein is a type I keratin that is specific for the inner root sheath of the hair follicle. This gene exists in a cluster with other keratin genes on chromosome 17q21. [provided by RefSeq, Jul 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000335552
  • ENSP00000334798
  • ENSG00000186393

Symbol
  • KRT25B
  • K25
  • K26
  • CK26
  • KRT25B
  • K25IRS2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.61
cellular component
0.6
gene perturbation
0.49
cell line
0.46
transcription factor
0.46


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.34   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 91   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.34   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 91   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (62)
KRT74
Tbio
Novelty:  0.12747273
Score:  0.923
Data Source:  STRINGDB
KRT71
Tbio
Novelty:  0.06565294
Score:  0.922
Data Source:  STRINGDB
KRT85
Tbio
Novelty:  0.09341199
Score:  0.921
Data Source:  STRINGDB
KRT73
Tdark
Novelty:  0.36334003
Score:  0.92
Data Source:  STRINGDB
KRT2
Tbio
Novelty:  0.01448252
Score:  0.918
Data Source:  STRINGDB
KRT6A
Tbio
Novelty:  0.00789111
Score:  0.914
Data Source:  STRINGDB
KRT6C
Tbio
Novelty:  0.11659743
Score:  0.914
Data Source:  STRINGDB
KRT39
Tdark
Novelty:  0.33252177
Score:  0.913
Data Source:  STRINGDB
KRT3
Tbio
Novelty:  0.00489796
Score:  0.913
Data Source:  STRINGDB
KRT81
Tbio
Novelty:  0.05514238
Score:  0.911
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Developmental Biology (R-HSA-1266738)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
Keratinization
Name
Explore in Pharos
Explore in Source
Developmental Biology
Keratinization
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
2
0
1
69.6
balding measurement
1
1
1
5.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1
69.6
balding measurement
1
5.7
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
keratin 26
VGNC:9356
468238
Macaque
keratin 26
702040
Mouse
MGI:2444913
320864
Rat
RGD:1303322
407758
Dog
keratin 26
VGNC:42524
491008
Species
Name
OMA
EggNOG
Inparanoid
Chimp
keratin 26
Macaque
keratin 26
Mouse
Rat
Dog
keratin 26
Publication Statistics
PubMed Score 30.34
PubMed score by year
PubTator Score 13.89
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title