Tbio NEGR1 Neuronal growth regulator 1

Protein Summary

Description

May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity).

Uniprot Accession IDs

• Q7Z3B1
• Q5VT21
• Q6UY06
• Q8N440
• Q8NAQ3

Gene Name

• NEGR1

Ensembl ID

• ENST00000306821
• ENSP00000305938
• ENSG00000172260
• ENST00000357731
• ENSP00000350364

Symbol

• IGLON4
• Ntra
• KILON
• IGLON4
• DMML2433

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	1
microRNA	0.86
protein domain	0.73
transcription factor binding site profile	0.7
disease	0.66

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 119.69   (req: < 5)

Gene RIFs: 35   (req: <= 3)

Antibodies: 182   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 119.69   (req: >= 5)

Gene RIFs: 35   (req: > 3)

Antibodies: 182   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0