Protein Summary
May play a role in motor coordination and exploratory behavior. This gene encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively spliced transcripts have been identified for this gene. [provided by RefSeq, Jan 2011]
- ENST00000367506
- ENSP00000356476
- ENSG00000121486
- C1orf25
- TRM1L
- TRM1L
- MST070
- C1orf25
- MSTP070
- bG120K12.3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cellular component | 0.9 | ||
histone modification site profile | 0.88 | ||
kinase perturbation | 0.88 | ||
interacting protein | 0.83 | ||
cell type or tissue | 0.77 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.72 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 81 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.72 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 81 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0