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Tdark
TMPRSS7
Transmembrane protease serine 7

Protein Summary
Description
Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000419127
  • ENSP00000411645
  • ENSG00000176040
  • ENST00000452346
  • ENSP00000398236
  • ENST00000617607
  • ENSP00000478830
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
cell line
0.69
cell type or tissue
0.5
PubMedID
0.5
tissue sample
0.38


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.97   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.97   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane serine protease 7
VGNC:10345
460580
Macaque
transmembrane protease, serine 7
709448
Mouse
MGI:2686594
208171
Rat
RGD:1304655
288118
Dog
transmembrane serine protease 7
VGNC:53088
487973
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane serine protease 7
Macaque
transmembrane protease, serine 7
Mouse
Rat
Dog
transmembrane serine protease 7
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q7RTY8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (10)
1 – 10 of 10
SSH2
Tbio
Family: Enzyme
Novelty: 0.05112042
Score: 0.541
Data Source: STRINGDB
CNTNAP5
Tbio
Novelty: 0.09102959
Score: 0.541
Data Source: STRINGDB
TMEM80
Tdark
Novelty: 0.69499586
Score: 0.487
Data Source: STRINGDB
DOCK5
Tbio
Novelty: 0.03153692
Score: 0.487
Data Source: STRINGDB
SPINT1
Tbio
Family: Enzyme
Novelty: 0.00930324
Score: 0.447
Data Source: STRINGDB
CFAP57
Tdark
Novelty: 0.33594432
Score: 0.446
Data Source: STRINGDB
SKIDA1
Tdark
Novelty: 0.28113063
Score: 0.43
Data Source: STRINGDB
ZNF676
Tdark
Family: TF
Novelty: 0.23073578
Score: 0.42
Data Source: STRINGDB
ZNF674
Tdark
Family: TF
Novelty: 0.29358331
Score: 0.416
Data Source: STRINGDB
ZNF57
Tdark
Family: TF
Novelty: 0.18919851
Score: 0.4
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.97

PubMed score by year
PubTator Score  1.03

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer