Tbio OLIG3 Oligodendrocyte transcription factor 3

Protein Summary

Description

May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.

Uniprot Accession IDs

• Q7RTU3
• Q8N8Q0
• Oligo3

Gene Name

• OLIG3

Ensembl ID

• ENST00000367734
• ENSP00000356708
• ENSG00000177468

Symbol

• BHLHB7
• BHLHE20
• Bhlhb7
• bHLHe20

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.76
cell type or tissue	0.71
biological process	0.61
PubMedID	0.61
tissue	0.59

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Basic Helix-loop-helix Transcription Factor / Oligodendrocyte Transcription Factor 3

Protein / Nucleic Acid Binding / Nuclease / Oligodendrocyte Transcription Factor 3

DTO Classes

Protein / Enzyme / Nuclease / Oligodendrocyte Transcription Factor 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.37   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 178   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.37   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 178   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0