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Tdark
TCF24
Transcription factor 24

Protein Summary
Description
Putative transcription factor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000563496
  • ENSP00000455444
  • ENSG00000261787

Symbol
  • TCF-24
  • bHLHa25
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.69
histone modification site profile
0.67
microRNA
0.67
tissue
0.48
gene perturbation
0.47


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.32   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 2   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.32   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 2   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
5.3
66.3
visceral adipose tissue measurement
1
1
1
38.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
5.3
66.3
visceral adipose tissue measurement
1
38.8
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Dog
transcription factor 24
VGNC:47195
610102
Opossum
transcription factor 24 [Source:HGNC Symbol;Acc:HGNC:32275]
Anole lizard
transcription factor 24
100566162
Species
Name
OMA
EggNOG
Inparanoid
Dog
transcription factor 24
Opossum
transcription factor 24 [Source:HGNC Symbol;Acc:HGNC:32275]
Anole lizard
transcription factor 24
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q7RTU0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (8)
1 – 8 of 8
TCF4
Tbio
Family:  TF
Novelty:  0.0019718
p_int:  0.854828501
p_wrong:  0.145171499
Score:  0.487
Data Source:  BioPlex,STRINGDB
MAD2L1BP
Tbio
Novelty:  0.48374717
Score:  0.724
Data Source:  STRINGDB
MXD3
Tbio
Family:  TF
Novelty:  0.07436584
Score:  0.573
Data Source:  STRINGDB
RIPPLY1
Tdark
Novelty:  0.11705603
Score:  0.511
Data Source:  STRINGDB
TBC1D8B
Tdark
Novelty:  0.35419125
Score:  0.48
Data Source:  STRINGDB
GRTP1
Tdark
Novelty:  0.8841166
Score:  0.478
Data Source:  STRINGDB
GATM
Tbio
Family:  Enzyme
Novelty:  0.00340356
Score:  0.418
Data Source:  STRINGDB
SZT2
Tbio
Novelty:  0.06995258
Score:  0.409
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.32

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer