KRT74
Keratin, type II cytoskeletal 74
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
microRNA | 0.58 | ||
cellular component | 0.55 | ||
cell line | 0.51 | ||
phenotype | 0.44 | ||
chemical | 0.41 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | Keratinization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Developmental Biology | ||||
Keratinization | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
keratinocyte carcinoma | 1 | 2 | 0 | 1.1 | 90.6 | ||||
4 | 1 | 1 | 1.2 | 81.2 | |||||
balding measurement | 1 | 2 | 2 | 72.5 | |||||
non-melanoma skin carcinoma | 1 | 1 | 0 | 1.3 | 54.4 | ||||
plasminogen activator inhibitor 1 measurement | 1 | 1 | 0 | 590.4 | 34.6 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
keratinocyte carcinoma | 0 | 1.1 | 90.6 | ||||
1 | 1.2 | 81.2 | |||||
balding measurement | 2 | 72.5 | |||||
non-melanoma skin carcinoma | 0 | 1.3 | 54.4 | ||||
plasminogen activator inhibitor 1 measurement | 0 | 590.4 | 34.6 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | keratin 74 | VGNC:14414 | 466992 | |||||
Macaque | keratin 74 | 699069 | ||||||
Dog | keratin 74 | VGNC:42531 | 486521 | |||||
Cow | keratin 74 | VGNC:30738 | 525034 | |||||
Pig | keratin 74 | 100511256 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | keratin 74 | |||||
Macaque | keratin 74 | |||||
Dog | keratin 74 | |||||
Cow | keratin 74 | |||||
Pig | keratin 74 | |||||
PMID | Year | Title |
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