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Tdark
ZNF627
Zinc finger protein 627

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.08   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 65   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.08   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (18)
PPP1R16B
Tbio
Family:  Enzyme
Novelty:  0.08773047
p_int:  0.999996683
p_ni:  0.000001286
p_wrong:  0.000002032
Score:  0.258
Data Source:  BioPlex,STRINGDB
VWCE
Tbio
Novelty:  0.09328341
p_int:  0.999995557
p_ni:  0.000003906
p_wrong:  5.37e-7
Data Source:  BioPlex
EFEMP1
Tbio
Novelty:  0.00574779
p_int:  0.999982907
p_ni:  0.000017088
p_wrong:  5e-9
Data Source:  BioPlex
CCNDBP1
Tbio
Novelty:  0.01527762
p_int:  0.999976107
p_ni:  0.000020488
p_wrong:  0.000003405
Score:  0.252
Data Source:  BioPlex,STRINGDB
FBLN2
Tbio
Novelty:  0.01340024
p_int:  0.99993122
p_ni:  0.000064042
p_wrong:  0.000004738
Data Source:  BioPlex
NELL2
Tbio
Family:  Enzyme
Novelty:  0.03760438
p_int:  0.999727401
p_ni:  0.00015842
p_wrong:  0.000114179
Score:  0.206
Data Source:  BioPlex,STRINGDB
DLK1
Tchem
Novelty:  0.00212394
p_int:  0.970845065
p_ni:  0.000338392
p_wrong:  0.028816543
Data Source:  BioPlex
GPR156
Tdark
Family:  GPCR
Novelty:  0.39183023
p_int:  0.855462327
p_ni:  0.000122063
p_wrong:  0.14441561
Data Source:  BioPlex
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.913
Data Source:  STRINGDB
OR13G1
Tdark
Family:  oGPCR
Novelty:  0.63690138
Score:  0.68
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diastolic blood pressure
1
1
1
15.8
antiphospholipid antibody measurement
1
1
0
2.2
14.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
diastolic blood pressure
1
15.8
antiphospholipid antibody measurement
0
2.2
14.2
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 627
100611580
Macaque
zinc finger protein 627
716820
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 627
Macaque
zinc finger protein 627
Publication Statistics
PubMed Score 3.08
PubMed score by year
PubTator Score 2.98
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title