Tdark FASTKD5 FAST kinase domain-containing protein 5, mitochondrial

Protein Summary

Description

Plays an important role in the processing of non-canonical mitochondrial mRNA precursors (PubMed:25683715).

Uniprot Accession IDs

• Q7L8L6
• Q96JN3
• Q9H5D1
• Q9H8Y3

Gene Name

• FASTKD5

Ensembl ID

• ENST00000380266
• ENSP00000369618
• ENSG00000215251

Symbol

• KIAA1792
• dJ1187M17.5

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.94
kinase perturbation	0.91
disease perturbation	0.87
tissue sample	0.72
transcription factor binding site profile	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.98   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 77   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.98   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0