FCRLA
Fc receptor-like A
Protein Summary
May be implicated in B-cell differentiation and lymphomagenesis. This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- ENST00000236938
- ENSP00000236938
- ENSG00000132185
- ENST00000294796
- ENSP00000294796
- ENST00000309691
- ENSP00000309596
- ENST00000349527
- ENSP00000294798
- ENST00000350710
- ENSP00000344808
- ENST00000367949
- ENSP00000356926
- ENST00000367953
- ENSP00000356930
- ENST00000367957
- ENSP00000356934
- ENST00000367959
- ENSP00000356936
- ENST00000540521
- ENSP00000442870
- ENST00000546024
- ENSP00000439838
- FCRL
- FCRL1
- FCRLM1
- FCRX
- FREB
- FCRL
- FCRX
- FREB
- FCRL1
- FCRLX
- FCRLb
- FCRLd
- FCRLe
- FCRLM1
- FCRLc1
- FCRLc2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell type or tissue | 0.93 | ||
tissue sample | 0.71 | ||
gene perturbation | 0.68 | ||
kinase perturbation | 0.48 | ||
tissue | 0.47 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 56.61 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 105 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 56.61 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 105 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0