You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
PDZD4
PDZ domain-containing protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000164640
  • ENSP00000164640
  • ENSG00000067840
  • ENST00000544474
  • ENSP00000442033

Symbol
  • KIAA1444
  • PDZK4
  • PDZRN4L
  • LU1
  • LNX5
  • PDZK4
  • PDZRN4L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.58
tissue sample
0.58
cell type or tissue
0.57
transcription factor
0.45
chemical
0.44


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 168.65   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 105   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 168.65   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
1
1
1
40.4
albumin:globulin ratio measurement
1
1
1
36.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
1
40.4
albumin:globulin ratio measurement
1
36.9
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
PDZ domain containing 4
VGNC:1515
104004027
Macaque
PDZ domain containing 4
697387
Mouse
MGI:2443483
245469
Rat
RGD:1561214
293856
Dog
PDZ domain containing 4
VGNC:44401
610856
Species
Name
OMA
EggNOG
Inparanoid
Chimp
PDZ domain containing 4
Macaque
PDZ domain containing 4
Mouse
Rat
Dog
PDZ domain containing 4
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q76G19-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (22)
1 – 10 of 22
ELF5
Tbio
Family:  TF
Novelty:  0.01490486
Score:  0.801
Data Source:  STRINGDB
BCAM
Tbio
Novelty:  0.01697541
Score:  0.714
Data Source:  STRINGDB
ELF3
Tbio
Family:  TF
Novelty:  0.00284335
Score:  0.712
Data Source:  STRINGDB
CALU
Tbio
Novelty:  0.01285123
Score:  0.666
Data Source:  STRINGDB
TAF3
Tbio
Family:  Epigenetic
Novelty:  0.05517331
Score:  0.636
Data Source:  STRINGDB
WFDC5
Tbio
Novelty:  0.0457192
Score:  0.54
Data Source:  STRINGDB
PDZD3
Tbio
Novelty:  0.08821289
Score:  0.514
Data Source:  STRINGDB
CNTN6
Tbio
Novelty:  0.00477805
Score:  0.505
Data Source:  STRINGDB
LIPN
Tbio
Family:  Enzyme
Novelty:  0.00135912
Score:  0.475
Data Source:  STRINGDB
GFOD1
Tdark
Family:  Enzyme
Novelty:  0.35031766
Score:  0.471
Data Source:  STRINGDB
Publication Statistics
PubMed Score  168.65

PubMed score by year
PubTator Score  46.16

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer