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Tbio
UTS2B
Urotensin-2B

Protein Summary
Description
Potent vasoconstrictor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000340524
  • ENSP00000340526
  • ENSG00000188958
  • ENST00000427544
  • ENSP00000398761

Symbol
  • URP
  • UTS2D
  • U2B
  • URP
  • UTS2D
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.57
cell line
0.55
tissue sample
0.55
histone modification site profile
0.54
tissue
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.09   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 116   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.09   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (171)
UTS2R
Tchem
Family:  GPCR
Novelty:  0.00865846
Score:  0.987
Data Source:  Reactome,STRINGDB
UTS2
Tbio
Novelty:  0.00279068
Score:  0.982
Data Source:  STRINGDB
QRFP
Tbio
Novelty:  0.02210773
Score:  0.944
Data Source:  STRINGDB
PROK2
Tbio
Novelty:  0.00512397
Score:  0.929
Data Source:  STRINGDB
NMS
Tbio
Novelty:  0.03324369
Score:  0.921
Data Source:  STRINGDB
F2RL3
Tchem
Family:  GPCR
Novelty:  0.01953308
Score:  0.921
Data Source:  STRINGDB
NPS
Tbio
Novelty:  0.00692108
Score:  0.918
Data Source:  STRINGDB
MCHR2
Tchem
Family:  GPCR
Novelty:  0.01191922
Score:  0.913
Data Source:  STRINGDB
ADRA1D
Tclin
Family:  GPCR
Novelty:  0.00203304
Score:  0.913
Data Source:  STRINGDB
EDNRB
Tclin
Family:  GPCR
Novelty:  0.00053875
Score:  0.911
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Class A/1 (Rhodopsin-like receptors) (R-HSA-373076)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Class A/1 (Rhodopsin-like receptors)
Reactome
G alpha (q) signalling events
Reactome
GPCR downstream signalling
Reactome
GPCR ligand binding
Reactome
Peptide ligand-binding receptors
Name
Explore in Pharos
Explore in Source
Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
GPCR downstream signalling
GPCR ligand binding
Peptide ligand-binding receptors
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
1
1
1
40.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
1
40.7
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
urotensin 2B
VGNC:12228
740781
Mouse
MGI:2677064
224065
Rat
RGD:727977
378939
Dog
urotensin 2B
VGNC:48216
608290
Horse
urotensin 2B
VGNC:24868
100059874
Species
Name
OMA
EggNOG
Inparanoid
Chimp
urotensin 2B
Mouse
Rat
Dog
urotensin 2B
Horse
urotensin 2B
Publication Statistics
PubMed Score 23.09
PubMed score by year
PubTator Score 25.42
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title