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Tbio
RPS27L
40S ribosomal protein S27-like

Protein Summary
Description
This gene encodes a protein sharing 96% amino acid similarity with ribosomal protein S27, which suggests the encoded protein may be a component of the 40S ribosomal subunit. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000330964
  • ENSP00000331019
  • ENSG00000185088
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.97
disease perturbation
0.96
transcription factor perturbation
0.94
transcription factor binding site profile
0.86
kinase perturbation
0.84


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.99   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 74   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.99   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (387)
RPS3A
Tbio
Novelty:  0.01009445
Score:  0.999
Data Source:  STRINGDB
RPS2
Tbio
Novelty:  0.00412313
Score:  0.999
Data Source:  STRINGDB
RPS4X
Tbio
Novelty:  0.01396038
Score:  0.999
Data Source:  STRINGDB
RPS6
Tbio
Novelty:  0.00122241
Score:  0.999
Data Source:  STRINGDB
RPL19
Tbio
Novelty:  0.00756385
Score:  0.999
Data Source:  STRINGDB
RPLP2
Tbio
Novelty:  0.00323155
Score:  0.999
Data Source:  STRINGDB
RPS13
Tbio
Novelty:  0.0019983
Score:  0.999
Data Source:  STRINGDB
RPL37A
Tbio
Novelty:  0.03475061
Score:  0.999
Data Source:  STRINGDB
RPL10A
Tbio
Novelty:  0.01747453
Score:  0.999
Data Source:  STRINGDB
RPL23
Tbio
Novelty:  0.02741113
Score:  0.999
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (39)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (R-HSA-72662)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 36
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Name
Explore in Pharos
Explore in Source
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (14)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations ()
No disease associations found
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
4
2
5
95.6
platelet count
3
3
3
2.4
95
high density lipoprotein cholesterol measurement
4
4
4
88.4
blood metabolite measurement
1
1
1
86.9
metabolite measurement
1
1
1
78
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
5
95.6
platelet count
3
2.4
95
high density lipoprotein cholesterol measurement
4
88.4
blood metabolite measurement
1
86.9
metabolite measurement
1
78
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein S27 like
100612661
Mouse
MGI:1915191
67941
Rat
RGD:1595396
681429
Dog
ribosomal protein S27
VGNC:53632
612291
Horse
ribosomal protein S27 like
100067253
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein S27 like
Mouse
Rat
Dog
ribosomal protein S27
Horse
ribosomal protein S27 like
Publication Statistics
PubMed Score 6.99
PubMed score by year
PubTator Score 3.32
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title