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Tbio
LARP4
La-related protein 4

Protein Summary
Description
RNA binding protein that binds to the poly-A tract of mRNA molecules (PubMed:21098120). Associates with the 40S ribosomal subunit and with polysomes (PubMed:21098120). Plays a role in the regulation of mRNA translation (PubMed:21098120). Plays a role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987, PubMed:27615744).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000293618
  • ENSP00000293618
  • ENSG00000161813
  • ENST00000347328
  • ENSP00000340901
  • ENST00000398473
  • ENSP00000381490
  • ENST00000429001
  • ENSP00000415464
  • ENST00000518444
  • ENSP00000429077
  • ENST00000522085
  • ENSP00000429781

Symbol
  • PP13296
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
microRNA
0.85
interacting protein
0.84
tissue sample
0.69
transcription factor binding site profile
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.64   (req: < 5)
Gene RIFs: 20   (req: <= 3)
Antibodies: 144   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.64   (req: >= 5)
Gene RIFs: 20   (req: > 3)
Antibodies: 144   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0