MED13L
Mediator of RNA polymerase II transcription subunit 13-like
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.91 | ||
transcription factor binding site profile | 0.9 | ||
transcription factor perturbation | 0.88 | ||
drug perturbation | 0.87 | ||
microRNA | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | PPARA activates gene expression | ||||
Reactome | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Developmental Biology | ||||
Metabolism | ||||
Metabolism of lipids | ||||
PPARA activates gene expression | ||||
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 1 | 2 | 67.4 | |||||
pulse pressure measurement | 1 | 1 | 1 | 45.2 | |||||
appendicular lean mass | 2 | 1 | 2 | 36.9 | |||||
1 | 1 | 0 | 1.1 | 36.5 | |||||
self reported educational attainment | 1 | 1 | 1 | 33.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 67.4 | |||||
pulse pressure measurement | 1 | 45.2 | |||||
appendicular lean mass | 2 | 36.9 | |||||
0 | 1.1 | 36.5 | |||||
self reported educational attainment | 1 | 33.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | mediator complex subunit 13 like | VGNC:8467 | 452281 | |||||
Macaque | mediator complex subunit 13 like | 713867 | ||||||
Mouse | MGI:2670178 | 76199 | ||||||
Rat | RGD:1305884 | 360817 | ||||||
Dog | mediator complex subunit 13 like | VGNC:43123 | 477496 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | mediator complex subunit 13 like | |||||
Macaque | mediator complex subunit 13 like | |||||
Mouse | ||||||
Rat | ||||||
Dog | mediator complex subunit 13 like | |||||
PMID | Year | Title |
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