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Tdark
CEFIP
Cardiac-enriched FHL2-interacting protein

Protein Summary
Description
Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374144
  • ENSP00000363259
  • ENSG00000177354

Symbol
  • C10orf71
  • CEFIP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.52   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 22   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.52   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Protein-Protein Interactions (18)
1 – 10 of 18
DYRK1B
Tchem
Family: Kinase
Novelty: 0.01960932
p_int: 0.999999972
p_ni: 2e-9
p_wrong: 2.6e-8
Score: 0.823
Data Source: BioPlex,STRINGDB
DYRK1A
Tchem
Family: Kinase
Novelty: 0.00226963
p_int: 0.999998062
p_ni: 0.000001938
Score: 0.873
Data Source: BioPlex,STRINGDB
DCAF7
Tbio
Novelty: 0.02609518
p_int: 0.997015701
p_ni: 0.002984297
p_wrong: 2e-9
Score: 0.82
Data Source: BioPlex,STRINGDB
FNTB
Tchem
Family: Enzyme
Novelty: 0.07434994
p_int: 0.970126384
p_ni: 0.029873579
p_wrong: 3.7e-8
Score: 0.704
Data Source: BioPlex,STRINGDB
FNTA
Tbio
Family: Enzyme
Novelty: 0.03163169
p_int: 0.92738229
p_ni: 0.072615339
p_wrong: 0.000002371
Score: 0.686
Data Source: BioPlex,STRINGDB
INSYN1
Tdark
Novelty: 1.45556076
Score: 0.818
Data Source: STRINGDB
DALRD3
Tdark
Novelty: 0.5378666
Score: 0.63
Data Source: STRINGDB
KIAA1755
Tdark
Novelty: 0.5138999
Score: 0.589
Data Source: STRINGDB
SUDS3
Tbio
Family: Enzyme
Novelty: 0.03837881
Score: 0.587
Data Source: STRINGDB
VSTM4
Tdark
Novelty: 0.46711608
Score: 0.586
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.52

PubMed score by year
PubTator Score  0.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer