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Tdark
TMPRSS11F
Transmembrane protease serine 11F

Protein Summary
Description
Probable serine protease.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356291
  • ENSP00000348639
  • ENSG00000198092

Symbol
  • HATL4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.85
protein domain
0.85
cell line
0.58
microRNA
0.51
tissue
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.92   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 33   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.92   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 33   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
influenza A (H1N1)
1
1
0
12.2
16.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
influenza A (H1N1)
0
12.2
16.9
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (7)
1 – 7 of 7
SPRTN
Tbio
Novelty: 0.0388393
Score: 0.656
Data Source: STRINGDB
ASGR1
Tbio
Novelty: 0.00209845
Score: 0.482
Data Source: STRINGDB
CLEC10A
Tbio
Novelty: 0.00656565
Score: 0.482
Data Source: STRINGDB
DNAH14
Tdark
Novelty: 0.28289652
Score: 0.448
Data Source: STRINGDB
DNAJB14
Tbio
Novelty: 0.6283107
Score: 0.428
Data Source: STRINGDB
ADAM32
Tdark
Family: Enzyme
Novelty: 0.36071191
Score: 0.424
Data Source: STRINGDB
TSPYL1
Tbio
Novelty: 0.06381144
Score: 0.4
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.92

PubMed score by year
PubTator Score  0.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer