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Tdark
TPRG1
Tumor protein p63-regulated gene 1 protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000345063
  • ENSP00000341031
  • ENSG00000188001
  • ENST00000433971
  • ENSP00000412547

Symbol
  • FAM79B
  • FAM79B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.85
cell type or tissue
0.65
cell line
0.64
microRNA
0.61
phenotype
0.6


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 47   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.33   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 47   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.2
31.2
1
1
0
1.2
24.8
cutaneous squamous cell carcinoma
1
1
1
15.9
1
1
0
1.1
11.1
1
1
0
1.2
4.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
31.2
0
1.2
24.8
cutaneous squamous cell carcinoma
1
15.9
0
1.1
11.1
0
1.2
4.3
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tumor protein p63 regulated 1
460928
Mouse
MGI:1918588
71338
Rat
RGD:1306226
360731
Dog
tumor protein p63 regulated 1
VGNC:47753
478672
Horse
tumor protein p63 regulated 1
VGNC:24444
100059710
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tumor protein p63 regulated 1
Mouse
Rat
Dog
tumor protein p63 regulated 1
Horse
tumor protein p63 regulated 1
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (23)
1 – 10 of 23
ICA1
Tbio
Novelty: 0.01241573
Score: 0.714
Data Source: STRINGDB
FAM124B
Tdark
Novelty: 0.96698909
Score: 0.679
Data Source: STRINGDB
PKP2
Tbio
Novelty: 0.00493803
Score: 0.668
Data Source: STRINGDB
BNIPL
Tbio
Novelty: 0.10839456
Score: 0.66
Data Source: STRINGDB
C9orf135
Tdark
Novelty: 1.45113559
Score: 0.644
Data Source: STRINGDB
ASAP2
Tbio
Novelty: 0.02744569
Score: 0.642
Data Source: STRINGDB
NXPE3
Tdark
Novelty: 1.5063521
Score: 0.592
Data Source: STRINGDB
RPP38
Tbio
Family: Enzyme
Novelty: 0.06387902
Score: 0.591
Data Source: STRINGDB
ADAL
Tbio
Family: Enzyme
Novelty: 0.02192886
Score: 0.589
Data Source: STRINGDB
IGSF3
Tbio
Novelty: 0.07528465
Score: 0.573
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.33

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer