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Tdark
TRIM67
Tripartite motif-containing protein 67

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366653
  • ENSP00000355613
  • ENSG00000119283
  • ENST00000449018
  • ENSP00000400163

Symbol
  • TNL
  • TNL
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
1
phenotype
0.75
gene perturbation
0.74
microRNA
0.7
biological process
0.57


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.81   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.81   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tripartite motif containing 67
VGNC:1704
469707
Macaque
tripartite motif containing 67
713730
Mouse
MGI:3045323
330863
Rat
RGD:1560667
307938
Dog
tripartite motif containing 67
VGNC:47834
608010
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tripartite motif containing 67
Macaque
tripartite motif containing 67
Mouse
Rat
Dog
tripartite motif containing 67
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6ZTA4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (35)
1 – 10 of 35
DCC
Tbio
Novelty:  0.01273911
Score:  0.738
Data Source:  STRINGDB
TRIM17
Tbio
Family:  Enzyme
Novelty:  0.00984948
Score:  0.727
Data Source:  STRINGDB
NEO1
Tbio
Novelty:  0.00625858
Score:  0.725
Data Source:  STRINGDB
IGDCC3
Tdark
Novelty:  0.01192143
Score:  0.677
Data Source:  STRINGDB
SDK2
Tdark
Novelty:  0.08867136
Score:  0.672
Data Source:  STRINGDB
TTC13
Tdark
Novelty:  2.24743499
Score:  0.663
Data Source:  STRINGDB
BBOX1
Tchem
Family:  Enzyme
Novelty:  0.00255489
Score:  0.646
Data Source:  STRINGDB
ARHGEF10
Tbio
Novelty:  0.04928387
Score:  0.632
Data Source:  STRINGDB
EFHD2
Tbio
Novelty:  0.04219879
Score:  0.602
Data Source:  STRINGDB
NLRP6
Tbio
Novelty:  0.01055512
Score:  0.571
Data Source:  STRINGDB
Publication Statistics
PubMed Score  48.81

PubMed score by year
PubTator Score  22.62

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer