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Tdark
SLC25A48
Solute carrier family 25 member 48

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000274513
  • ENSP00000274513
  • ENSG00000145832
  • ENST00000412661
  • ENSP00000413049
  • ENST00000433282
  • ENSP00000399834
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.98
cellular component
0.64
cell line
0.62
histone modification site profile
0.54
disease
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.67   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 37   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.67   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 37   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
TPM2
Tbio
Novelty:  0.00406572
p_int:  0.994010195
p_ni:  0.005989804
p_wrong:  1e-9
Score:  0.181
Data Source:  BioPlex,STRINGDB
RNF11
Tbio
Novelty:  0.04766714
p_int:  0.874549677
p_ni:  0.001738804
p_wrong:  0.123711519
Score:  0.228
Data Source:  BioPlex,STRINGDB
EEF2
Tchem
Novelty:  0.00064095
p_int:  0.764772671
p_ni:  0.235227329
Score:  0.267
Data Source:  BioPlex,STRINGDB
ANKRD40
Tdark
Novelty:  1.06633958
p_int:  0.756620567
p_ni:  0.243379433
Score:  0.188
Data Source:  BioPlex,STRINGDB
SLC47A2
Tchem
Family:  Transporter
Novelty:  0.01171254
Score:  0.599
Data Source:  STRINGDB
SLC25A17
Tbio
Family:  Transporter
Novelty:  0.00601179
Score:  0.581
Data Source:  STRINGDB
SLC16A9
Tbio
Family:  Transporter
Novelty:  0.06564904
Score:  0.553
Data Source:  STRINGDB
TNFAIP8L2
Tbio
Novelty:  0.01938521
Score:  0.538
Data Source:  STRINGDB
TMEM88
Tbio
Novelty:  0.14612337
Score:  0.524
Data Source:  STRINGDB
HSPB9
Tbio
Novelty:  0.09680405
Score:  0.523
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
2
2
2
57.1
eosinophil percentage of leukocytes
1
1
1
3.5
hip geometry
1
1
1
1.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
2
57.1
eosinophil percentage of leukocytes
1
3.5
hip geometry
1
1.7
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 25 member 48
VGNC:8641
471641
Mouse
MGI:2145373
328258
Rat
RGD:1563703
361206
Dog
solute carrier family 25 member 48
VGNC:46318
481518
Horse
solute carrier family 25 member 48
VGNC:23119
100072690
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 25 member 48
Mouse
Rat
Dog
solute carrier family 25 member 48
Horse
solute carrier family 25 member 48
Publication Statistics
PubMed Score 0.67
PubMed score by year
PubTator Score 0.06
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title