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Tbio
MFSD6
Major facilitator superfamily domain-containing protein 6

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000281416
  • ENSP00000281416
  • ENSG00000151690
  • ENST00000392328
  • ENSP00000376141

Symbol
  • MMR2
  • MMR2
  • hMMR2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.97
histone modification site profile
0.79
PubMedID
0.74
transcription factor
0.65
virus perturbation
0.64


Related Tools
RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 61.85   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 103   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 61.85   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 103   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lifestyle measurement
1
1
1
79.3
insomnia measurement
2
1
0
1
44
platelet count
1
1
1
21
glomerular filtration rate
1
1
0
5.5
6.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lifestyle measurement
1
79.3
insomnia measurement
0
1
44
platelet count
1
21
glomerular filtration rate
0
5.5
6.9
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
major facilitator superfamily domain containing 6
VGNC:2016
459830
Macaque
major facilitator superfamily domain containing 6
710476
Mouse
MGI:1922925
98682
Rat
RGD:1562317
301388
Dog
major facilitator superfamily domain containing 6
VGNC:43205
488445
Species
Name
OMA
EggNOG
Inparanoid
Chimp
major facilitator superfamily domain containing 6
Macaque
major facilitator superfamily domain containing 6
Mouse
Rat
Dog
major facilitator superfamily domain containing 6
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6ZSS7-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (71)
1 – 10 of 71
ZNF384
Tbio
Family: TF
Novelty: 0.01412476
Score: 0.815
Data Source: STRINGDB
NEMP2
Tdark
Novelty: 1.47547409
Score: 0.724
Data Source: STRINGDB
MFSD12
Tbio
Novelty: 0.20519777
Score: 0.7
Data Source: STRINGDB
MIGA1
Tbio
Novelty: 0.08346483
Score: 0.694
Data Source: STRINGDB
MFSD9
Tdark
Novelty: 0.98582986
Score: 0.682
Data Source: STRINGDB
CSGALNACT2
Tbio
Family: Enzyme
Novelty: 0.0770692
Score: 0.678
Data Source: STRINGDB
TMTC2
Tbio
Novelty: 0.17232458
Score: 0.658
Data Source: STRINGDB
C19orf12
Tbio
Novelty: 0.02182564
Score: 0.657
Data Source: STRINGDB
MFSD13A
Tdark
Novelty: 0.39321369
Score: 0.649
Data Source: STRINGDB
HMOX2
Tchem
Family: Enzyme
Novelty: 0.00180703
Score: 0.641
Data Source: STRINGDB
Publication Statistics
PubMed Score  61.85

PubMed score by year
PubTator Score  26.58

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer