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Tbio
CLEC17A
C-type lectin domain family 17, member A

Protein Summary
Description
Cell surface receptor which may be involved in carbohydrate-mediated communication between cells in the germinal center. Binds glycans with terminal alpha-linked mannose or fucose residues.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339847
  • ENSP00000341620
  • ENSG00000187912
  • ENST00000417570
  • ENSP00000393719
  • ENST00000547437
  • ENSP00000450065
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.58
microRNA
0.57
cell line
0.47
disease
0.4
protein complex
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.33   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.33   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (10)
RASAL3
Tbio
Novelty:  0.22098972
Score:  0.633
Data Source:  STRINGDB
FAM102B
Tdark
Novelty:  1.44024802
Score:  0.623
Data Source:  STRINGDB
TRAPPC5
Tdark
Novelty:  0.22558077
Score:  0.605
Data Source:  STRINGDB
NLRC3
Tbio
Novelty:  0.0205634
Score:  0.479
Data Source:  STRINGDB
CD163
Tbio
Novelty:  0.0007415
Score:  0.474
Data Source:  STRINGDB
CD83
Tbio
Novelty:  0.00138653
Score:  0.452
Data Source:  STRINGDB
CD86
Tclin
Novelty:  0.00029965
Score:  0.442
Data Source:  STRINGDB
UNC119B
Tbio
Novelty:  0.26468307
Score:  0.42
Data Source:  STRINGDB
CD80
Tclin
Novelty:  0.00031181
Score:  0.416
Data Source:  STRINGDB
FAM102A
Tdark
Novelty:  0.32284443
Score:  0.414
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
risk-taking behaviour
2
2
2
54.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
risk-taking behaviour
2
54.3
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
C-type lectin domain containing 17A [Source:HGNC Symbol;Acc:HGNC:34520]
Dog
C-type lectin domain containing 17A
VGNC:39329
610758
Pig
C-type lectin domain containing 17A
100514755
Species
Name
OMA
EggNOG
Inparanoid
Macaque
C-type lectin domain containing 17A [Source:HGNC Symbol;Acc:HGNC:34520]
Dog
C-type lectin domain containing 17A
Pig
C-type lectin domain containing 17A
Publication Statistics
PubMed Score 11.33
PubMed score by year
PubTator Score 4.90
PubTator score by year
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Related Publications
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PMID
Year
Title