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Tdark
ZNF493
Zinc finger protein 493

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339914
  • ENSP00000340651
  • ENSG00000196268
  • ENST00000355504
  • ENSP00000347691
  • ENST00000392288
  • ENSP00000376110
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.58
cell line
0.57
transcription factor
0.57
histone modification site profile
0.53
microRNA
0.49


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.82   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 59   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.82   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 59   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (9)
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.917
Data Source:  STRINGDB
CENPH
Tbio
Novelty:  0.02845079
Score:  0.795
Data Source:  STRINGDB
SLC43A3
Tbio
Family:  Transporter
Novelty:  0.13959933
Score:  0.559
Data Source:  STRINGDB
AJAP1
Tbio
Novelty:  0.05553491
Score:  0.474
Data Source:  STRINGDB
LMO3
Tbio
Novelty:  0.03437083
Score:  0.466
Data Source:  STRINGDB
PIEZO1
Tchem
Family:  IC
Novelty:  0.00374633
Score:  0.443
Data Source:  STRINGDB
GALNT7
Tbio
Family:  Enzyme
Novelty:  0.05328171
Score:  0.44
Data Source:  STRINGDB
CDK12
Tchem
Family:  Kinase
Novelty:  0.0119925
Score:  0.407
Data Source:  STRINGDB
SLC19A1
Tchem
Family:  Transporter
Novelty:  0.00536763
Score:  0.405
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell density measurement
1
1
1
49.5
1
1
0
1.2
12.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell density measurement
1
49.5
0
1.2
12.4
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 1.82
PubMed score by year
PubTator Score 0.10
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title