Tbio DGAT2L6 Diacylglycerol O-acyltransferase 2-like protein 6

Protein Summary

Description

Probable acyltransferase uses fatty acyl-CoA as substrate (By similarity). Has no wax synthase activity to produce wax esters. This gene is a member of the diacylglycerol acyltransferase 2 family. The encoded protein is a putative acyltransferase and is most likely involved in the synthesis of di- or triacylglycerol, however its substrate specificity is currently unknown. [provided by RefSeq, Feb 2015]

Uniprot Accession IDs

• Q6ZPD8
• Q6IEE2

Gene Name

• DGAT2L6

Ensembl ID

• ENST00000333026
• ENSP00000328036
• ENSG00000184210

Symbol

• DC3
• DC3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
metabolite	0.83
cell type or tissue	0.73
tissue sample	0.57
cellular component	0.46
disease	0.43

Protein Classes

PANTHER Classes

Protein / Transferase / Acyltransferase / Diacylglycerol O-acyltransferase 2-like Protein 6

DTO Classes

Protein / Enzyme / Transferase / Acyltransferase / Diacylglycerol O-acyltransferase 2-like Protein 6

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.39   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 38   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.39   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 38   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0