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Tbio
DGAT2L6
Diacylglycerol O-acyltransferase 2-like protein 6

Protein Summary
Description
Probable acyltransferase uses fatty acyl-CoA as substrate (By similarity). Has no wax synthase activity to produce wax esters. This gene is a member of the diacylglycerol acyltransferase 2 family. The encoded protein is a putative acyltransferase and is most likely involved in the synthesis of di- or triacylglycerol, however its substrate specificity is currently unknown. [provided by RefSeq, Feb 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000333026
  • ENSP00000328036
  • ENSG00000184210

Symbol
  • DC3
  • DC3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
metabolite
0.83
cell type or tissue
0.73
tissue sample
0.57
cellular component
0.46
disease
0.43


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 38   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 38   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
diacylglycerol O-acyltransferase 2 like 6
VGNC:10402
465973
Macaque
diacylglycerol O-acyltransferase 2 like 6
694889
Mouse
MGI:3045268
668257
Rat
RGD:1596935
678749
Dog
diacylglycerol O-acyltransferase 2 like 6
VGNC:39914
607544
Species
Name
OMA
EggNOG
Inparanoid
Chimp
diacylglycerol O-acyltransferase 2 like 6
Macaque
diacylglycerol O-acyltransferase 2 like 6
Mouse
Rat
Dog
diacylglycerol O-acyltransferase 2 like 6
Pathways (5)
Acyl chain remodeling of DAG and TAG (R-HSA-1482883)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Acyl chain remodeling of DAG and TAG
Reactome
Glycerophospholipid biosynthesis
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Phospholipid metabolism
Name
Explore in Pharos
Explore in Source
Acyl chain remodeling of DAG and TAG
Glycerophospholipid biosynthesis
Metabolism
Metabolism of lipids
Phospholipid metabolism
Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Experiment (EXP)
Reactome
Protein-Protein Interactions (34)
1 – 10 of 34
TMEM255B
Tdark
Novelty: 1.57149427
Score: 0.75
Data Source: STRINGDB
TMEM68
Tdark
Novelty: 0.61508475
Score: 0.599
Data Source: STRINGDB
OSTC
Tbio
Family: Enzyme
Novelty: 0.06699106
Score: 0.545
Data Source: STRINGDB
LPCAT4
Tdark
Family: Enzyme
Novelty: 0.246654
Score: 0.535
Data Source: STRINGDB
FA2H
Tbio
Family: Enzyme
Novelty: 0.00449208
Score: 0.535
Data Source: STRINGDB
SLC22A14
Tdark
Family: Transporter
Novelty: 0.3340737
Score: 0.52
Data Source: STRINGDB
OTUD6A
Tbio
Novelty: 0.52996035
Score: 0.52
Data Source: STRINGDB
ELOVL1
Tbio
Novelty: 0.03178348
Score: 0.518
Data Source: STRINGDB
GDPD2
Tbio
Family: Enzyme
Novelty: 0.07190804
Score: 0.508
Data Source: STRINGDB
MBOAT7
Tbio
Family: Enzyme
Novelty: 0.01861411
Score: 0.502
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.29

PubMed score by year
PubTator Score  17.63

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer