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Tdark
TMEM182
Transmembrane protein 182

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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.74   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 18   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.74   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
2
2
2
79
electrocardiography
1
1
8
30.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
2
79
electrocardiography
8
30.9
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 182
VGNC:399
745787
Macaque
transmembrane protein 182
712344
Mouse
MGI:1923725
381339
Rat
RGD:1563696
501129
Dog
transmembrane protein 182
VGNC:47507
611413
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 182
Macaque
transmembrane protein 182
Mouse
Rat
Dog
transmembrane protein 182
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (24)
1 – 10 of 24
LGALS3
Tchem
Novelty: 0.00032754
p_int: 0.982722169
p_ni: 0.017277831
Score: 0.189
Data Source: BioPlex,STRINGDB
TM6SF1
Tdark
Novelty: 0.40815928
Score: 0.748
Data Source: STRINGDB
TSPAN33
Tbio
Novelty: 0.17463296
Score: 0.675
Data Source: STRINGDB
LMOD3
Tbio
Novelty: 0.06244763
Score: 0.607
Data Source: STRINGDB
UBQLN3
Tdark
Novelty: 0.25889138
Score: 0.589
Data Source: STRINGDB
ZNF738
Tdark
Novelty: 6.56360276
Score: 0.57
Data Source: STRINGDB
MCTP2
Tbio
Novelty: 0.1142276
Score: 0.557
Data Source: STRINGDB
SMIM23
Tdark
Novelty: 1.06937018
Score: 0.531
Data Source: STRINGDB
CDH15
Tbio
Novelty: 0.01904376
Score: 0.524
Data Source: STRINGDB
ZMAT4
Tdark
Novelty: 0.31281969
Score: 0.521
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.74

PubMed score by year
PubTator Score  1.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer