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Tdark
ZNF704
Zinc finger protein 704

Protein Summary
Description
Transcription factor which binds to RE2 sequence elements in the MYOD1 enhancer.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000327835
  • ENSP00000331462
  • ENSG00000164684

Symbol
  • Gig1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.75
transcription factor perturbation
0.68
transcription factor binding site profile
0.66
microRNA
0.65
tissue sample
0.63


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.12   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 48   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.12   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 48   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
viral load
1
1
1
68
testosterone measurement
2
1
2
66
sex hormone-binding globulin measurement
3
2
3
63.9
heel bone mineral density
1
2
2
57.1
Cannabis use
1
1
1
28.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
viral load
1
68
testosterone measurement
2
66
sex hormone-binding globulin measurement
3
63.9
heel bone mineral density
2
57.1
Cannabis use
1
28.1
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 704
VGNC:757
464252
Macaque
zinc finger protein 704
700514
Mouse
MGI:2180715
170753
Rat
RGD:1563869
310233
Dog
zinc finger protein 704
VGNC:48803
610881
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 704
Macaque
zinc finger protein 704
Mouse
Rat
Dog
zinc finger protein 704
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6ZNC4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (36)
1 – 10 of 36
BTRC
Tbio
Novelty:  0.00293475
p_int:  0.999996697
p_ni:  0.000003303
Data Source:  BioPlex
FBXW11
Tbio
Novelty:  0.0715377
p_int:  0.999983661
p_ni:  0.000016339
Score:  0.168
Data Source:  BioPlex,STRINGDB
SAP30L
Tbio
Family:  Enzyme
Novelty:  0.20174722
p_int:  0.999903956
p_ni:  0.000094918
p_wrong:  0.000001126
Score:  0.65
Data Source:  BioPlex,STRINGDB
SIN3A
Tbio
Novelty:  0.00747207
p_int:  0.999866907
p_ni:  0.000133093
Score:  0.655
Data Source:  BioPlex,STRINGDB
SUDS3
Tbio
Family:  Enzyme
Novelty:  0.03837881
p_int:  0.999844561
p_ni:  0.000155439
Score:  0.803
Data Source:  BioPlex,STRINGDB
ING2
Tchem
Family:  Epigenetic
Novelty:  0.02424031
p_int:  0.99967899
p_ni:  0.000321008
p_wrong:  2e-9
Score:  0.828
Data Source:  BioPlex,STRINGDB
ARID4A
Tbio
Family:  TF; Epigenetic
Novelty:  0.04953333
p_int:  0.999669663
p_ni:  0.000330337
Score:  0.554
Data Source:  BioPlex,STRINGDB
SAP30
Tbio
Family:  Enzyme
Novelty:  0.03474176
p_int:  0.999454617
p_ni:  0.000545383
Score:  0.682
Data Source:  BioPlex,STRINGDB
SAP130
Tdark
Family:  Enzyme
Novelty:  1.85084032
p_int:  0.99944117
p_ni:  0.00055883
Score:  0.534
Data Source:  BioPlex,STRINGDB
ARID4B
Tbio
Family:  TF; Epigenetic
Novelty:  0.04182223
p_int:  0.999150014
p_ni:  0.000849986
Score:  0.518
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  4.12

PubMed score by year
PubTator Score  1.87

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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