RNF111
E3 ubiquitin-protein ligase Arkadia
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.85 | ||
biological process | 0.83 | ||
microRNA | 0.81 | ||
molecular function | 0.67 | ||
kinase perturbation | 0.66 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing: Ubiquitination & Proteasome degradation | ||||
Reactome | Class I MHC mediated antigen processing & presentation | ||||
Reactome | DNA Repair | ||||
Reactome | Downregulation of SMAD2/3:SMAD4 transcriptional activity | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Antigen processing: Ubiquitination & Proteasome degradation | ||||
Class I MHC mediated antigen processing & presentation | ||||
DNA Repair | ||||
Downregulation of SMAD2/3:SMAD4 transcriptional activity | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
3 | 5 | 7 | 1.1 | 60.2 | |||||
serum metabolite measurement | 1 | 1 | 2 | 56 | |||||
phosphatidylethanolamine measurement | 1 | 2 | 2 | 47.5 | |||||
pulse pressure measurement | 1 | 1 | 1 | 46.9 | |||||
platelet crit | 1 | 1 | 1 | 33.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
7 | 1.1 | 60.2 | |||||
serum metabolite measurement | 2 | 56 | |||||
phosphatidylethanolamine measurement | 2 | 47.5 | |||||
pulse pressure measurement | 1 | 46.9 | |||||
platelet crit | 1 | 33.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ring finger protein 111 | VGNC:1887 | 453477 | |||||
Macaque | ring finger protein 111 | 701953 | ||||||
Mouse | MGI:1934919 | 93836 | ||||||
Rat | RGD:1310097 | 300813 | ||||||
Dog | ring finger protein 111 | VGNC:45621 | 478323 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ring finger protein 111 | |||||
Macaque | ring finger protein 111 | |||||
Mouse | ||||||
Rat | ||||||
Dog | ring finger protein 111 | |||||
PMID | Year | Title |
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