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Tdark
ZFP2
Zinc finger protein 2 homolog

Protein Summary
Description
Probable transcription factor involved in neuronal differentiation and/or phenotypic maintenance.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361362
  • ENSP00000354453
  • ENSG00000198939
  • ENST00000520301
  • ENSP00000430980
  • ENST00000523286
  • ENSP00000430531

Symbol
  • ZNF751
  • zfp-2
  • ZNF751
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.74
gene perturbation
0.68
cell type or tissue
0.59
cell line
0.45
tissue sample
0.45


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.38   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 44   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.38   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
refractive error measurement
1
1
1
56.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
refractive error measurement
1
56.1
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ZFP2 zinc finger protein
VGNC:13617
100609319
Macaque
ZFP2 zinc finger protein
703114
Mouse
MGI:99167
22678
Rat
RGD:1562610
497897
Dog
ZFP2 zinc finger protein
VGNC:49827
474648
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ZFP2 zinc finger protein
Macaque
ZFP2 zinc finger protein
Mouse
Rat
Dog
ZFP2 zinc finger protein
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6ZN57-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (16)
1 – 10 of 16
ZNF71
Tdark
Family: TF
Novelty: 0.24703192
p_int: 0.999999969
p_wrong: 3.1e-8
Score: 0.193
Data Source: BioPlex,STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
GEMIN8
Tbio
Novelty: 0.19515325
Score: 0.638
Data Source: STRINGDB
NMT2
Tchem
Family: Enzyme
Novelty: 0.04826835
Score: 0.612
Data Source: STRINGDB
C12orf50
Tdark
Novelty: 7.97059878
Score: 0.569
Data Source: STRINGDB
SETD3
Tbio
Family: Epigenetic
Novelty: 0.07150702
Score: 0.494
Data Source: STRINGDB
TTPAL
Tdark
Novelty: 1.21133441
Score: 0.484
Data Source: STRINGDB
MED6
Tbio
Family: Enzyme
Novelty: 0.05215086
Score: 0.483
Data Source: STRINGDB
BCAS2
Tbio
Novelty: 0.05425016
Score: 0.463
Data Source: STRINGDB
PDE5A
Tclin
Family: Enzyme
Novelty: 0.00032205
Score: 0.454
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.38

PubMed score by year
PubTator Score  1.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer