Tbio AEBP2 Zinc finger protein AEBP2

Protein Summary

Description

DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.

Uniprot Accession IDs

• Q6ZN18
• Q59FS5
• Q6ZN62
• Q96BG3

Gene Name

• AEBP2

Ensembl ID

• ENST00000266508
• ENSP00000266508
• ENSG00000139154
• ENST00000360995
• ENSP00000354267
• ENST00000398864
• ENSP00000381840

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.91
molecular function	0.91
transcription factor perturbation	0.88
transcription factor binding site profile	0.85
cell type or tissue	0.79

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.01   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 181   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.01   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 181   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0