Tdark EML6 Echinoderm microtubule-associated protein-like 6

Protein Summary

Description

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

Uniprot Accession IDs

• Q6ZMW3
• A8MUB5
• B6ZDG7
• EMAP-6

Gene Name

• EML6

Ensembl ID

• ENST00000356458
• ENSP00000348842
• ENSG00000214595

Symbol

• EML5L

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
trait	0.86
microRNA	0.8
transcription factor binding site profile	0.77
transcription factor	0.67

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.8   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 8   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.8   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0