ADAMTSL5
ADAMTS-like protein 5
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.85 | ||
tissue sample | 0.68 | ||
transcription factor perturbation | 0.68 | ||
histone modification site profile | 0.67 | ||
molecular function | 0.67 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Defective B3GALTL causes Peters-plus syndrome (PpS) | ||||
Reactome | Disease | ||||
Reactome | Diseases associated with O-glycosylation of proteins | ||||
Reactome | Diseases of glycosylation | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Defective B3GALTL causes Peters-plus syndrome (PpS) | ||||
Disease | ||||
Diseases associated with O-glycosylation of proteins | ||||
Diseases of glycosylation | ||||
Metabolism of proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hemoglobin measurement | 1 | 1 | 1 | 13.5 | |||||
hematocrit | 1 | 1 | 1 | 13.5 | |||||
pulse pressure measurement | 1 | 1 | 1 | 12.6 | |||||
Urinary retention | 1 | 1 | 0 | 7.8 | 3.7 | ||||
response to radiation | 1 | 1 | 0 | 7.8 | 3.7 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hemoglobin measurement | 1 | 13.5 | |||||
hematocrit | 1 | 13.5 | |||||
pulse pressure measurement | 1 | 12.6 | |||||
Urinary retention | 0 | 7.8 | 3.7 | ||||
response to radiation | 0 | 7.8 | 3.7 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ADAMTS like 5 | VGNC:2085 | 742967 | |||||
Macaque | ADAMTS like 5 | 721290 | ||||||
Mouse | MGI:1913798 | 66548 | ||||||
Dog | ADAMTS like 5 | VGNC:37609 | 485082 | |||||
Horse | ADAMTS like 5 | VGNC:50328 | 100060620 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ADAMTS like 5 | |||||
Macaque | ADAMTS like 5 | |||||
Mouse | ||||||
Dog | ADAMTS like 5 | |||||
Horse | ADAMTS like 5 | |||||
PMID | Year | Title |
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