Tbio CERS6 Ceramide synthase 6

Protein Summary

Description

May be involved in sphingolipid synthesis or its regulation.

Uniprot Accession IDs

• Q6ZMG9
• Q32M63
• Q8N617
• CerS6

Gene Name

• CERS6

Ensembl ID

• ENST00000305747
• ENSP00000306579
• ENSG00000172292
• ENST00000392687
• ENSP00000376453

Symbol

• LASS6
• CERS5
• LASS6

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	0.97
kinase perturbation	0.96
transcription factor perturbation	0.94
transcription factor binding site profile	0.8
virus perturbation	0.79

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 84.23   (req: < 5)

Gene RIFs: 35   (req: <= 3)

Antibodies: 211   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 84.23   (req: >= 5)

Gene RIFs: 35   (req: > 3)

Antibodies: 211   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0