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Tdark
SPNS3
Protein spinster homolog 3

Protein Summary
Description
Sphingolipid transporter.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355530
  • ENSP00000347721
  • ENSG00000182557
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.93
tissue sample
0.64
gene perturbation
0.55
cellular component
0.44
phenotype
0.43


Related Tools
RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.27   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.27   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
sphingolipid transporter 3 (putative)
VGNC:10349
454445
Macaque
sphingolipid transporter 3 (putative) [Source:HGNC Symbol;Acc:HGNC:28433]
Mouse
MGI:1924827
77577
Rat
RGD:1561884
497946
Dog
sphingolipid transporter 3 (putative)
VGNC:53449
606839
Species
Name
OMA
EggNOG
Inparanoid
Chimp
sphingolipid transporter 3 (putative)
Macaque
sphingolipid transporter 3 (putative) [Source:HGNC Symbol;Acc:HGNC:28433]
Mouse
Rat
Dog
sphingolipid transporter 3 (putative)
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6ZMD2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (33)
1 – 10 of 33
CLCC1
Tbio
Family: IC
Novelty: 0.06584842
p_int: 0.807033927
p_ni: 0.192966073
Score: 0.455
Data Source: BioPlex,STRINGDB
SLC22A1
Tchem
Family: Transporter
Novelty: 0.00427728
Score: 0.908
Data Source: STRINGDB
SVOP
Tbio
Novelty: 0.0830639
Score: 0.641
Data Source: STRINGDB
MFSD9
Tdark
Novelty: 0.98582986
Score: 0.635
Data Source: STRINGDB
SVOPL
Tdark
Novelty: 0.46448049
Score: 0.63
Data Source: STRINGDB
MFSD13A
Tdark
Novelty: 0.39321369
Score: 0.628
Data Source: STRINGDB
MFSD6L
Tdark
Novelty: 1.62242256
Score: 0.624
Data Source: STRINGDB
MFSD3
Tdark
Novelty: 0.71247324
Score: 0.592
Data Source: STRINGDB
SLC22A23
Tbio
Family: Transporter
Novelty: 0.23405744
Score: 0.59
Data Source: STRINGDB
MFSD5
Tdark
Novelty: 0.58146966
Score: 0.577
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.27

PubMed score by year
PubTator Score  0.22

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer