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Tbio
IGSF10
Immunoglobulin superfamily member 10

Protein Summary
Description
Involved in the control of early migration of neurons expressing gonadotropin-releasing hormone (GNRH neurons) (By similarity). May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000282466
  • ENSP00000282466
  • ENSG00000152580

Symbol
  • CMF608
  • CMF608
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.99
gene perturbation
0.81
cell line
0.67
disease perturbation
0.62
virus perturbation
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.13   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 58   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.13   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 58   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (22)
ADGRL3
Tbio
Family:  GPCR
Novelty:  0.00268343
Score:  0.685
Data Source:  STRINGDB
ADGRL1
Tbio
Family:  GPCR
Novelty:  0.00957739
Score:  0.685
Data Source:  STRINGDB
ADGRL2
Tbio
Family:  GPCR
Novelty:  0.00985539
Score:  0.685
Data Source:  STRINGDB
LRRC63
Tdark
Novelty:  3.01647797
Score:  0.565
Data Source:  STRINGDB
PCED1B
Tdark
Family:  Enzyme
Novelty:  0.42975161
Score:  0.527
Data Source:  STRINGDB
STK32B
Tchem
Family:  Kinase
Novelty:  0.1892431
Score:  0.522
Data Source:  STRINGDB
PDZRN4
Tdark
Novelty:  0.1881035
Score:  0.517
Data Source:  STRINGDB
TMEM154
Tdark
Novelty:  0.08935925
Score:  0.502
Data Source:  STRINGDB
MPZL3
Tbio
Novelty:  0.25092947
Score:  0.49
Data Source:  STRINGDB
PDS5B
Tbio
Novelty:  0.00295057
Score:  0.478
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
1
1
42.3
anti-Epstein Barr virus antibody measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
42.3
anti-Epstein Barr virus antibody measurement
1
21.5
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin superfamily member 10
VGNC:6294
470968
Macaque
immunoglobulin superfamily member 10
709661
Mouse
MGI:1923481
242050
Rat
RGD:735030
310448
Dog
immunoglobulin superfamily member 10
VGNC:41913
477114
Species
Name
OMA
EggNOG
Inparanoid
Chimp
immunoglobulin superfamily member 10
Macaque
immunoglobulin superfamily member 10
Mouse
Rat
Dog
immunoglobulin superfamily member 10
Publication Statistics
PubMed Score 7.13
PubMed score by year
PubTator Score 1.84
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title