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Tbio
RAB11FIP1
Rab11 family-interacting protein 1

Protein Summary
Description
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis. This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000287263
  • ENSP00000287263
  • ENSG00000156675
  • ENST00000330843
  • ENSP00000331342
  • ENST00000524118
  • ENSP00000430680

Symbol
  • RCP
  • RCP
  • NOEL1A
  • rab11-FIP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.96
transcription factor perturbation
0.88
microRNA
0.81
drug perturbation
0.71
cellular component
0.7


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.7   (req: < 5)
Gene RIFs: 30   (req: <= 3)
Antibodies: 186   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.7   (req: >= 5)
Gene RIFs: 30   (req: > 3)
Antibodies: 186   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RAB11 family interacting protein 1
VGNC:10324
472740
Mouse
MGI:1923017
75767
Horse
RAB11 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30265]
Cow
RAB11 family interacting protein 1
VGNC:33616
518839
Opossum
RAB11 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30265]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RAB11 family interacting protein 1
Mouse
Horse
RAB11 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30265]
Cow
RAB11 family interacting protein 1
Opossum
RAB11 family interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30265]
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q6WKZ4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (8)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (69)
1 – 10 of 69
RAB11A
Tbio
Family: Enzyme
Novelty: 0.00153551
p_int: 0.999999948
p_ni: 5.2e-8
Score: 0.966
Data Source: BioPlex,STRINGDB
RAB11B
Tbio
Family: Enzyme
Novelty: 0.00557558
p_int: 0.999999796
p_ni: 2.04e-7
Score: 0.947
Data Source: BioPlex,STRINGDB
RELT
Tbio
Novelty: 0.07977949
p_int: 0.992678056
p_ni: 0.007321944
Score: 0.303
Data Source: BioPlex,STRINGDB
NOLC1
Tbio
Novelty: 0.01922261
p_int: 0.981780075
p_ni: 0.018219925
Score: 0.737
Data Source: BioPlex,STRINGDB
YWHAZ
Tbio
Novelty: 0.00210582
p_int: 0.892707514
p_ni: 0.107292486
Score: 0.156
Data Source: BioPlex,STRINGDB
PIP4K2A
Tbio
Family: Kinase
Novelty: 0.01130885
p_int: 0.806584342
p_ni: 0.193415658
Score: 0.2
Data Source: BioPlex,STRINGDB
YWHAG
Tbio
Novelty: 0.00845572
p_int: 0.777795953
p_ni: 0.222204047
Data Source: BioPlex
RAB11FIP2
Tbio
Novelty: 0.06330621
Score: 0.88
Data Source: STRINGDB
RAB25
Tbio
Family: Enzyme
Novelty: 0.01889483
Score: 0.872
Data Source: STRINGDB
PLPBP
Tbio
Family: Enzyme
Novelty: 0.04352366
Score: 0.869
Data Source: STRINGDB
Publication Statistics
PubMed Score  23.70

PubMed score by year
PubTator Score  29.82

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer