Tbio ALKAL1 ALK and LTK ligand 1

Protein Summary

Description

Ligand for receptor tyrosine kinase LTK and perhaps receptor tyrosine kinase ALK; activation of ALK is reported conflictingly.

Uniprot Accession IDs

• Q6UXT8
• B7ZMG9

Gene Name

• ALKAL1

Ensembl ID

• ENST00000358543
• ENSP00000351345
• ENSG00000196711
• ENST00000523939
• ENSP00000430953

Symbol

• FAM150A
• AUGA
• AUGB
• FAM150A
• UNQ9433

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0
biological term	0
cell line	0
cell type or tissue	0
cellular component	0

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.68   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 22   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.68   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0