You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
PAMR1
Inactive serine protease PAMR1

Protein Summary
Description
May play a role in regeneration of skeletal muscle.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000615849
  • ENSP00000479260
  • ENSG00000149090
  • ENST00000619888
  • ENSP00000483703
  • ENST00000622144
  • ENSP00000482899

Symbol
  • RAMP
  • RAMP
  • FP938
  • DKFZP586H2123
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
gene perturbation
0.68
cell type or tissue
0.64
trait
0.61
tissue
0.55


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.24   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.24   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
3
2
2
1.1
45.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
1.1
45.6
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
peptidase domain containing associated with muscle regeneration 1
VGNC:3240
451123
Macaque
peptidase domain containing associated with muscle regeneration 1
717140
Mouse
MGI:2445082
210622
Dog
peptidase domain containing associated with muscle regeneration 1
VGNC:44251
483426
Horse
peptidase domain containing associated with muscle regeneration 1
VGNC:21145
100067176
Species
Name
OMA
EggNOG
Inparanoid
Chimp
peptidase domain containing associated with muscle regeneration 1
Macaque
peptidase domain containing associated with muscle regeneration 1
Mouse
Dog
peptidase domain containing associated with muscle regeneration 1
Horse
peptidase domain containing associated with muscle regeneration 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6UXH9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (33)
1 – 10 of 33
SLC1A2
Tchem
Family:  Transporter
Novelty:  0.00086733
Score:  0.728
Data Source:  STRINGDB
MINDY3
Tbio
Novelty:  0.02865765
Score:  0.658
Data Source:  STRINGDB
SRPX
Tbio
Novelty:  0.1173202
Score:  0.572
Data Source:  STRINGDB
NEBL
Tbio
Novelty:  0.02155964
Score:  0.57
Data Source:  STRINGDB
KNDC1
Tdark
Novelty:  0.1459108
Score:  0.551
Data Source:  STRINGDB
ACOT11
Tbio
Family:  Enzyme
Novelty:  0.0400726
Score:  0.547
Data Source:  STRINGDB
LDLRAD3
Tbio
Novelty:  0.16667448
Score:  0.542
Data Source:  STRINGDB
MICAL3
Tbio
Family:  Enzyme
Novelty:  0.13432068
Score:  0.532
Data Source:  STRINGDB
C8orf76
Tdark
Novelty:  1.38782332
Score:  0.527
Data Source:  STRINGDB
ZHX1-C8orf76
Tdark
Novelty:  4.53406141
Score:  0.527
Data Source:  STRINGDB
Publication Statistics
PubMed Score  18.24

PubMed score by year
PubTator Score  67.1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer