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Tbio
LAYN
Layilin

Protein Summary
Description
Receptor for hyaluronate.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375614
  • ENSP00000364764
  • ENSG00000204381
  • ENST00000375615
  • ENSP00000364765
  • ENST00000436913
  • ENSP00000392942
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.7
histone modification site profile
0.57
cellular component
0.47
metabolite
0.45
tissue
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.38   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 326   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.38   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 326   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (19)
1 – 10 of 19
TLN1
Tbio
Novelty:  0.00803981
Score:  0.894
Data Source:  STRINGDB
TLN2
Tbio
Novelty:  0.0284423
Score:  0.862
Data Source:  STRINGDB
NF2
Tbio
Novelty:  0.00055092
Score:  0.649
Data Source:  STRINGDB
HAPLN1
Tbio
Novelty:  0.00458172
Score:  0.618
Data Source:  STRINGDB
HMMR
Tchem
Novelty:  0.0039196
Score:  0.575
Data Source:  STRINGDB
TLE2
Tbio
Novelty:  0.03922169
Score:  0.538
Data Source:  STRINGDB
PRSS12
Tchem
Novelty:  0.02726265
Score:  0.533
Data Source:  STRINGDB
SMOC1
Tbio
Novelty:  0.03819681
Score:  0.513
Data Source:  STRINGDB
MAGEH1
Tbio
Novelty:  0.00457617
Score:  0.503
Data Source:  STRINGDB
PNRC1
Tbio
Novelty:  0.00705875
Score:  0.492
Data Source:  STRINGDB
Gene Ontology Terms (6)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HGNC
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
6
5
0
1
88.2
Eczema
2
2
0
1.1
71.6
2
2
0
1.1
71.6
3
2
0
1.1
64.9
diet measurement
3
2
3
32.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1
88.2
Eczema
0
1.1
71.6
0
1.1
71.6
0
1.1
64.9
diet measurement
3
32.8
Find similar targets by:
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
layilin
VGNC:1086
451539
Macaque
layilin
710211
Mouse
MGI:2685357
244864
Rat
RGD:1564444
500996
Dog
layilin
VGNC:42601
489411
Species
Name
OMA
EggNOG
Inparanoid
Chimp
layilin
Macaque
layilin
Mouse
Rat
Dog
layilin
Publication Statistics
PubMed Score 16.38
PubMed score by year
PubTator Score 10.30
PubTator score by year