Tbio CWC27 Spliceosome-associated protein CWC27 homolog

Protein Summary

Description

As part of the spliceosome, plays a role in pre-mRNA splicing (PubMed:29360106). Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity (PubMed:20676357).

Uniprot Accession IDs

• Q6UX04
• O60529
• O60530
• Q96EM3

Gene Name

• CWC27

Ensembl ID

• ENST00000381070
• ENSP00000370460
• ENSG00000153015

Symbol

• SDCCAG10
• RPSKA
• NY-CO-10
• SDCCAG10
• SDCCAG-10

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.83
histone modification site profile	0.76
tissue sample	0.74
transcription factor binding site profile	0.69
interacting protein	0.57

Protein Classes

PANTHER Classes

Protein / Isomerase / Spliceosome-associated Protein Cwc27 Homolog

DTO Classes

Protein / Enzyme / Isomerase / Peptidyl-prolyl Cis-trans Isomerase Cwc27 Homolog

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.7   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 123   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.7   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0