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Tbio
FAM198B
Protein FAM198B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296530
  • ENSP00000296530
  • ENSG00000164125
  • ENST00000393807
  • ENSP00000377396
  • ENST00000585682
  • ENSP00000465976
  • ENST00000592057
  • ENSP00000466873

Symbol
  • C4orf18
  • ENED
  • ENED
  • AD021
  • AD036
  • C4orf18
  • FAM198B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.91
transcription factor perturbation
0.88
cell type or tissue
0.74
small molecule perturbation
0.62
kinase perturbation
0.6


Related Tools
GENEVA
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ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 73   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 198 member B
VGNC:2991
736769
Macaque
family with sequence similarity 198 member B
700615
Mouse
MGI:1915909
68659
Rat
RGD:735075
310540
Dog
family with sequence similarity 198 member B
VGNC:40646
100685456
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 198 member B
Macaque
family with sequence similarity 198 member B
Mouse
Rat
Dog
family with sequence similarity 198 member B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6UWH4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
LIFEdb
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (25)
1 – 10 of 25
FAM20A
Tbio
Family: Enzyme
Novelty: 0.03742119
Score: 0.832
Data Source: STRINGDB
FAM20B
Tdark
Family: Enzyme
Novelty: 0.07347685
Score: 0.798
Data Source: STRINGDB
FAM20C
Tbio
Family: Enzyme
Novelty: 0.00318966
Score: 0.757
Data Source: STRINGDB
FJX1
Tbio
Novelty: 0.07957088
Score: 0.755
Data Source: STRINGDB
CCDC34
Tbio
Novelty: 0.31079723
Score: 0.639
Data Source: STRINGDB
LRRC69
Tdark
Novelty: 3.28767123
Score: 0.575
Data Source: STRINGDB
MICALCL
Tdark
Novelty: 0.53179355
Score: 0.569
Data Source: STRINGDB
LRRC46
Tdark
Novelty: 1.159245
Score: 0.549
Data Source: STRINGDB
LRRTM3
Tbio
Novelty: 0.18633527
Score: 0.494
Data Source: STRINGDB
ZNF608
Tdark
Novelty: 0.18575706
Score: 0.474
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.86

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer