Tbio TBPL2 TATA box-binding protein-like protein 2

Protein Summary

Description

Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).

Uniprot Accession IDs

• Q6SJ96
• Q17RU8
• TBP-like protein 2

Gene Name

• TBPL2

Ensembl ID

• ENST00000247219
• ENSP00000247219
• ENSG00000182521

Symbol

• TBP2
• TRF3
• TBP2
• TRF3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.58
biological process	0.53
cell type or tissue	0.5
tissue	0.47
cell line	0.44

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Tata-binding Transcription Factor / Tata Box-binding Protein-like Protein 2

Protein / Nucleic Acid Binding / Tata Box-binding Protein-like Protein 2

DTO Classes

Protein / Transcription Factor / Tata-binding Transcription Factor / Tata Box-binding Protein-like Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.67   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 116   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.67   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 116   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0