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Tbio
SLC30A9
Zinc transporter 9

Protein Summary
Description
Acts as a zinc transporter involved in intracellular zinc homeostasis (PubMed:28334855). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000264451
  • ENSP00000264451
  • ENSG00000014824

Symbol
  • C4orf1
  • HUEL
  • HUEL
  • ZNT9
  • GAC63
  • C4orf1
  • BILAPES
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.9
histone modification site profile
0.85
interacting protein
0.85
transcription factor perturbation
0.84
kinase perturbation
0.76


Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.51   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 142   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.51   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
unipolar depression
4
3
1
1
70.2
alcohol consumption measurement
5
3
5
64.9
1
1
0
1
42.3
neuroticism measurement
2
2
0
5.6
37.3
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
unipolar depression
1
1
70.2
alcohol consumption measurement
5
64.9
0
1
42.3
neuroticism measurement
0
5.6
37.3
1
24.5
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 30 member 9
VGNC:7723
461188
Macaque
solute carrier family 30 member 9
702177
Mouse
MGI:1923690
109108
Rat
RGD:1593180
498358
Dog
solute carrier family 30 member 9
VGNC:46354
482117
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 30 member 9
Macaque
solute carrier family 30 member 9
Mouse
Rat
Dog
solute carrier family 30 member 9
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q6PML9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (15)
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Model (ISM)
NTNU_SB
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (60)
1 – 10 of 60
COX4I1
Tbio
Family:  Enzyme
Novelty:  0.00208873
p_int:  0.999609431
p_ni:  0.000390569
Data Source:  BioPlex
COX5A
Tbio
Family:  Enzyme
Novelty:  0.02110193
p_int:  0.995319715
p_ni:  0.004680285
Score:  0.309
Data Source:  BioPlex,STRINGDB
VNN2
Tbio
Novelty:  0.02286648
p_int:  0.971228463
p_ni:  0.028771536
p_wrong:  1e-9
Score:  0.212
Data Source:  BioPlex,STRINGDB
TBC1D15
Tbio
Novelty:  0.11296513
p_int:  0.959127347
p_ni:  0.040872653
Score:  0.225
Data Source:  BioPlex,STRINGDB
ERGIC3
Tbio
Novelty:  0.11095443
p_int:  0.955891698
p_ni:  0.044108302
Data Source:  BioPlex
HLA-DQA1
Tbio
Novelty:  0.00077488
p_int:  0.806324905
p_ni:  0.193675095
Score:  0.187
Data Source:  BioPlex,STRINGDB
HLA-DRA
Tbio
Novelty:  0.0060214
p_int:  0.759393474
p_ni:  0.240606526
Data Source:  BioPlex
SLC30A6
Tbio
Family:  Transporter
Novelty:  0.06083299
Score:  0.865
Data Source:  STRINGDB
SLC30A5
Tbio
Family:  Transporter
Novelty:  0.02432633
Score:  0.865
Data Source:  STRINGDB
SLC30A7
Tbio
Family:  Transporter
Novelty:  0.02998245
Score:  0.861
Data Source:  STRINGDB
Publication Statistics
PubMed Score  17.51

PubMed score by year
PubTator Score  6.9

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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